TZIELD Indication for :15 seconds
We are being compensated by Sanofi to share our story.
Disclaimer:
Amanda and William are being compensated for sharing their story in this video.
AMANDA ON-CAMERA
My name is Amanda and I live in Charlotte, North Carolina. I am a mom to two children, William and Jenna. Our son, William, is an avid track and cross-country athlete.
WILLIAM ON-CAMERA
I found running my freshman year. I just started out going with a couple friends that I met through the neighborhood. We just moved here and I was like, "I got to find a pathway to find some friends," and so I built a really tight friend group through running. Now I'm starting to chase the goals of getting faster times and working down in time to see how far I can take my running career.
Disclaimer:
William is a TZIELD patient. Individual results may vary.
Please see Important Safety Information at the conclusion of this video and full Prescribing Information/Medication Guide on this webpage.
AMANDA
Our family has no history of type 1 diabetes. That all changed in September of 2020 when our daughter Jenna at 11 years old was diagnosed with type 1 diabetes. We were completely shocked. She was in full DKA in the hospital for five days, was incredibly sick.
I learned a lot about Type 1 Diabetes as my daughter was diagnosed. And one of the things that I learned was that other family members are up to 15 times more likely to have Type 1 Diabetes when there is a direct relative. So that was very critical to me to learn more about screening and if my husband, myself, or my son might also have those autoantibodies.
So from the screening, we learned that our son, William, had multiple autoantibodies that indicated Type 1 Diabetes. We also learned that he had abnormal blood glucose levels, also known as dysglycemia.
Disclaimer:
Patient stories reflect the real-life experiences of persons diagnosed with Stage 2 T1D who have been prescribed TZIELD. However, individual experiences may vary. Patient stories are not necessarily representative of what another person using TZIELD may experience.
When we received news that William had stage 2 of type 1 diabetes, we were devastated. We were still in the midst of learning about our daughter's diagnosis. We were adjusting her numbers, going through all the things involved in a new diagnosis of type 1. We were mentally, emotionally, physically exhausted. We were concerned for her future and how her current childhood would look for her. So, to learn that our son also would be facing a similar path was just not the news that we had hoped for.
With diabetes, often we wake up in the middle of the night to manage a high or a low. And I thought to myself fairly soon I'm going to wonder, is this my daughter or is this my son? What if it's both of them at the same time? How are we going to manage that?
As soon as I heard about TZIELD, I was very excited to talk to William's doctor. I had a lot of questions about side effects, but I really wanted to learn more.
Disclaimer:
What is TZIELD? TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body can’t make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 8 years of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels and do not have type 2 diabetes. It is not known if TZIELD is safe and effective in children under 8 years of age.
His doctor explained that the most common side effects were rash, leukopenia, which is a decrease in white blood cell count and headache. I also learned that TZIELD may cause serious side effects, including cytokine release syndrome and lymphopenia, which is a decrease in white blood cells.
Disclaimer:
The most common side effects of TZIELD include rash, leukopenia (decrease in white blood cell counts) and headache. TZIELD may cause serious side effects, including cytokine release syndrome and lymphopenia, which is a decrease in white blood cells.
Our COMPASS Navigator was great. Often, I confess, I would call him nearly every day, and he was always happy to receive my calls, listen, and answer any questions we had.
The actual infusion process was a very careful and thought out procedure.
Disclaimer:
Your healthcare provider will do blood tests to check your liver and your complete blood counts before you start treatment and during treatment with TZIELD.
We received pre-medications, they did lab work and they were closely monitoring William at all times, before, during, and after his treatments.
Disclaimer:
For the first 5 days of treatment, your healthcare provider will give you medicines by mouth before starting your TZIELD infusion. These medicines include ibuprofen, naproxen or other pain relievers such as acetaminophen, an antihistamine, and an anti-nausea medicine. These medicines may help reduce symptoms of cytokine release syndrome (CRS) such as a fever, headache, muscle and joint pain, or nausea.
The first week of William’s infusions, we were there for four or five hours. The second week was much quicker. Two, two and a half hours at most.
While William was being treated, I passed my time by talking with nurses and staff, and I did some work on my laptop as well. And we just had a good time enjoying each other's company. It was nice mother-son time.
Disclaimer:
TZIELD is given by a healthcare provider through a needle place in a vein (intravenous infusion) in your arm.
TZIELD was definitely the right choice for William and for our family because we have lived with one child already who's been diagnosed with stage three of type one diabetes. Her constant glucose monitoring and life managing highs and lows is exceedingly difficult and relentless. For our son to be able to avoid any portion of time living with stage three of type one diabetes is wonderful.
Disclaimer:
Individual results may vary.
WILLIAM
If I was able to go back in time and tell myself one thing, I wouldn't change a thing.
AMANDA
It has been one year since Williams' treatment with TZIELD. When I think about the hours, months, and so much countless time that our daughter has spent managing her stage three type one diabetes, that William has been able to delay that portion of his life has been so worth it.
My advice to families living with T1D is to be bold and to be brave. Ask your questions, do your research. Find out, get screened, use that information and consider all of your options.
Disclaimer:
Talk to your doctor to see if TZIELD may be right for you or your loved one.
INDICATION AND ISI with VO
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