Patient Support Program

A father sitting on the couch with his daughter and both are looking at her tablet

Katie, TZIELD patient with daughter

By your side throughout the treatment journey

TZIELD COMPASS is a dedicated patient support program designed to help and support you or your loved one at every step of the treatment journey, helping to make the TZIELD experience as seamless as possible.

Just one call can connect you with:

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Personalized support

TZIELD COMPASS can answer questions about the program and resources, including how your insurance benefits work, and help you determine your out-of-pocket costs

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Financial support options

TZIELD COMPASS can provide information about which financial support programs you may be eligible for depending on your diagnosis and insurance type

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Treatment information

TZIELD COMPASS can help you understand where to get TZIELD infusions depending on your insurance and other factors, plus check in with you throughout treatment and once treatment is completed

How to get started with

TZIELD COMPASS logo

After you or your loved one has been prescribed TZIELD, enroll in TZIELD COMPASS in
3 steps:

Step 1

Complete the Start Form with your doctor.

TZIELD COMPASS Start Form
Step 2

Your doctor will submit the completed form. Only your doctor's office can enroll you in TZIELD COMPASS. The enrollment form requires a patient's or guardian's signature, which can be done in person or digitally.

Step 3

Once enrolled, TZIELD COMPASS will give you a phone call within 1 business day.

This program is intended to help with the cost of TZIELD and its infusion administration only. It does not help with the cost of other medicines you take at the same time as TZIELD or with other facility fees. Not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any stat pharmaceutical assistance programs. Eligibility requirements and terms and conditions apply. See here for more information on the terms and conditions.

More TZIELD COMPASS Resources

TZIELD COMPASS offers additional resources to support you or your loved one throughout treatment.

TZIELD Copay Program

With the TZIELD Copay Program, eligible patients with commercial health insurance may pay as little as $0* copay for treatment. Terms and conditions apply.

Connect with a TZIELD mentor

If you’ve spoken with your doctor about TZIELD, or have been prescribed treatment, you can register to speak one-on-one with a TZIELD Mentor, a real patient or caregiver of a TZIELD patient. Reach out to TZIELD COMPASS at 1-844-778-2246 Monday through Friday, 8 AM-8 PM ET, or COMPASS@sanofi.com to hear firsthand stories and learn from their personal experiences with TZIELD

Beginning your TZIELD Journey

Once you and your doctor have decided that TZIELD is right for you or your loved one, this resource will guide you through the process to help make the TZIELD treatment experience as smooth as possible from start to finish.

*The TZIELD Copay Program is not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any state pharmaceutical assistance programs. Not valid where prohibited by law, taxed, or restricted. Sanofi reserves the right to rescind or amend this offer, eligibility, and terms of use at any time without notice. Upon registration, patients receive all Program details.

Frequently Asked Questions

Have more questions?

For more information about TZIELD COMPASS Support or how to enroll, call 1-844-778-2246 Monday through Friday, 8 AM-8 PM ET or email COMPASS@sanofi.com.

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Actor portrayal

Important Safety Information and Indication

What is the most important information I should know about TZIELD? TZIELD may cause serious side effects. These including:
  • Viral Reactivation. Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are common viruses that may stay inactive in your body after an initial infection. TZIELD may cause these viruses to become active again which, especially in patients with a weakened immune system, can become serious and potentially life-threatening. These viral reactivations can happen during treatment with TZIELD and up to 2 months after your last dose. Your healthcare provider will test you for active EBV and CMV infections before treatment with TZIELD. Contact your healthcare provider right away if you develop symptoms of an infection during or after treatment with TZIELD (such as fever, swollen glands, or fatigue).
  • Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea (with or without vomiting), feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD. 
  • Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes.

Your healthcare provider will do blood tests to check for active infections, verify your liver function and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection or viral reactivation, or if your blood counts stay too low.  

What should I tell my healthcare provider before receiving TZIELD? Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:
  • have any of the conditions or symptoms listed in the section “What is the most important information I should know about TZIELD?”
  • have a weakened immune system, including if you have Down syndrome.
  • have a serious infection or an infection that does not go away or keeps coming back (chronic). 
  • have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your healthcare provider that you are receiving treatment with TZIELD before receiving a vaccine.
  • are pregnant or plan to become pregnant. TZIELD may harm your unborn baby.  Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy.  

If you become pregnant while taking TZIELD, you are encouraged to report your pregnancy to us at our Adverse Event reporting line at 1-800-633-1610 or visit https://ae.reporting.sanofi.

  • are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TZIELD? The most common side effects of TZIELD include:
  • decrease in white blood cell counts
  • vomiting
  • rash
  • diarrhea
  • headache

These are not all of the possible side effects of TZIELD. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to us at 1-800-633-1610 or www.fda.gov/medwatch or 1-800-FDA-1088.

Please see full Prescribing Information, including Risk of SERIOUS SIDE EFFECTS and Medication Guide.

What is TZIELD?

TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body cannot make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 1 year of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes or other forms of diabetes.

It is not known if TZIELD is safe and effective in children under 1 years of age.

Important Safety Information and Indication

What is the most important information I should know about TZIELD? TZIELD may cause serious side effects. These including:
  • Viral Reactivation. Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are common viruses that may stay inactive in your body after an initial infection. TZIELD may cause these viruses to become active again which, especially in patients with a weakened immune system, can become serious and potentially life-threatening. These viral reactivations can happen during treatment with TZIELD and up to 2 months after your last dose. Your healthcare provider will test you for active EBV and CMV infections before treatment with TZIELD. Contact your healthcare provider right away if you develop symptoms of an infection during or after treatment with TZIELD (such as fever, swollen glands, or fatigue).
  • Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea (with or without vomiting), feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD. 
  • Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes.

Your healthcare provider will do blood tests to check for active infections, verify your liver function and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection or viral reactivation, or if your blood counts stay too low.  

What should I tell my healthcare provider before receiving TZIELD? Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:
  • have any of the conditions or symptoms listed in the section “What is the most important information I should know about TZIELD?”
  • have a weakened immune system, including if you have Down syndrome.
  • have a serious infection or an infection that does not go away or keeps coming back (chronic). 
  • have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your healthcare provider that you are receiving treatment with TZIELD before receiving a vaccine.
  • are pregnant or plan to become pregnant. TZIELD may harm your unborn baby.  Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy.  

If you become pregnant while taking TZIELD, you are encouraged to report your pregnancy to us at our Adverse Event reporting line at 1-800-633-1610 or visit https://ae.reporting.sanofi.

  • are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TZIELD? The most common side effects of TZIELD include:
  • decrease in white blood cell counts
  • vomiting
  • rash
  • diarrhea
  • headache

These are not all of the possible side effects of TZIELD. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to us at 1-800-633-1610 or www.fda.gov/medwatch or 1-800-FDA-1088.

Please see full Prescribing Information, including Risk of SERIOUS SIDE EFFECTS and Medication Guide.

What is TZIELD?

TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body cannot make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 1 year of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes or other forms of diabetes.

It is not known if TZIELD is safe and effective in children under 1 years of age.