A father and his young daughter sitting on a couch and looking at a tablet

TZIELD COMPASS SUPPORT PROGRAM

A TZIELD COMPASS Navigator is ready to help

Through our personalized program, a COMPASS Navigator can connect you with tools and resources, information on financial assistance options, and one-on-one support from the day you are enrolled. This means you can get the help you need, when you need it to support you during the treatment process.

TZIELD COMPASS Navigators are here to help with:

A clipboard

Personalized Support

TZIELD COMPASS Navigators can answer questions about the program and resources, including how your insurance benefits work, and help you determine your out-of-pocket costs

A dollar sign

TZIELD Copay Program

Navigators can provide information about the TZIELD Copay Program,*
where eligible commercially insured patients may pay as little as $0, and help you explore other financial assistance options that may be available to you

A location pin

Treatment Information

Navigators can help you understand where to get TZIELD infusions depending on your insurance and other factors, plus check in with you once treatment is completed

Aubri, a TZIELD® (teplizumab-mzwv) patient, smiling and sitting on the couch eating popcorn with her mother and caregiver, MollyAubri, TZIELD patient with caregiver

Get started

Download the TZIELD COMPASS start form

For more information about TZIELD COMPASS Support, call 1-844-778-2246 Monday through Friday, 8 am-8 pm ET.

TZIELD COMPASS is a patient support program that helps eligible patients to gain access to TZIELD and provides them with education and resources related to TZIELD.

This program is intended to help with the cost of TZIELD and its infusion administration only. It does not help with the cost of other medicines you take at the same time as TZIELD or with other facility fees. Not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any stat pharmaceutical assistance programs. Eligibility requirements and terms and conditions apply. See here for more information on the terms and conditions.

John: Getting connected with a TZIELD COMPASS Navigator

John found himself in uncharted waters after his Stage 2 type 1 diabetes diagnosis, but a TZIELD COMPASS Navigator helped steer him through his T1D treatment journey.

John is a Patient Ambassador sponsored by Sanofi.

TZIELD indication card
John VO:

“I am being compensated by Sanofi to share my story.”

John, TZIELD Patient
[Compensated by Sanofi]
“Fortunately, I visited the TZIELD website and got connected with the COMPASS Navigator program. Within a day of me reaching out, I had a phone conversation with a Navigator, and she was so helpful. She was able to explain to me about the process, help me understand the paperwork needed, got connected with my endocrinologist clinic, and helped me understand the timelines of what things looked like next.”

“Getting connected with the COMPASS Navigator and talking through with someone who understood TZIELD and what I was going through was impactful to me. I felt like I was in a circumstance that I had never experienced before, so being able to have that advocate and who understood the experience and leaned into my experience and heard what I was saying was really important to me and made a difference in my experience with my healthcare journey.”

See John’s full story on the Real Talk About Type 1 & TZIELD page

[TZIELD logo]

What is TZIELD?
TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body can’t make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 8 years of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes.

It is not known if TZIELD is safe and effective in children under 8 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TZIELD?

TZIELD may cause serious side effects. These include:

  • Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea, feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD
  • Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes

Your healthcare provider will do blood tests to check your liver and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection, or if your blood counts stay too low.

What should I tell my healthcare provider before receiving TZIELD?

Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:

  • have a serious infection or an infection that does not go away or keeps coming back
  • have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your doctor that you are receiving TZIELD before receiving a vaccine
  • are pregnant or plan to become pregnant. TZIELD may harm your unborn baby. Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy
  • are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TZIELD?

The most common side effects of TZIELD include:

  • rash
  • leukopenia (decrease in white blood cell counts)
  • headache

These are not all of the possible side effects of TZIELD. Talk to your healthcare provider for more information, and tell them about any side effects you notice. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

Please see [accompanying] Medication Guide and Prescribing Information.

MAT-US-2306423-v2.0-01/2024

More real stories...
John, a TZIELD® (teplizumab-mzwv) patient, with his dog outdoors
John’s Story

Always active, John was stunned to learn he had...

Casandra, a TZIELD® (teplizumab-mzwv) patient, with her young daughter
Casandra’s story

Casandra was eager to delay progressing to Stage 3...

Aubri, a TZIELD® (teplizumab-mzwv) patient, smiling and sitting on the couch eating popcorn with her mother and caregiver, Molly
Molly & Aubri

Molly works at a diabetes care center and learned by...

Katie, a TZIELD® (teplizumab) patient
Katie’s story

An active wife and mom, Katie was shocked and...

Will, a TZIELD® (teplizumab-mzwv) patient, with his mother and caregiver, Amanda, cooking in the kitchen
Amanda & Will

Managing her daughter’s T1D diagnosis was already...

SEE ALLSEE LESS

HOW TO GET STARTED WITH

TZIELD COMPASS logo

After you or your loved one has been prescribed TZIELD, enroll in TZIELD COMPASS in three steps:


Step 1:

Complete the START Form with your doctor

Step 2:

Your doctor will submit the completed form

Step 3:

Once enrolled, a COMPASS Navigator will give you a phone call within 1 business day from the TZIELD COMPASS Support Program

Beginning Your TZIELD Journey

Once you and your doctor have decided that TZIELD is right for you or your loved one, this resource will guide you through the process to help make the TZIELD treatment experience as smooth as possible from start to finish.

IMPORTANT SAFETY INFORMATION What is the most important information I should know about TZIELD? TZIELD may cause serious side effects. These include:
  • Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea, feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD
  • Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes

Your healthcare provider will do blood tests to check your liver and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection, or if your blood counts stay too low.

What should I tell my healthcare provider before receiving TZIELD? Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:
  • have a serious infection or an infection that does not go away or keeps coming back
  • have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your doctor that you are receiving TZIELD before receiving a vaccine
  • are pregnant or plan to become pregnant. TZIELD may harm your unborn baby. Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy
  • are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TZIELD? The most common side effects of TZIELD include:
  • rash
  • leukopenia (decrease in white blood cell counts)
  • headache

These are not all of the possible side effects of TZIELD. Talk to your healthcare provider for more information, and tell them about any side effects you notice. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

Please see Medication Guide and Prescribing Information.

What is TZIELD?

TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body can’t make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 8 years of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes.

It is not known if TZIELD is safe and effective in children under 8 years of age.

IMPORTANT SAFETY INFORMATION AND APPROVED USE

What is the most important information I should know about TZIELD? TZIELD may cause serious side effects. These include:
  • Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea, feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD
  • Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes

Your healthcare provider will do blood tests to check your liver and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection, or if your blood counts stay too low.

What should I tell my healthcare provider before receiving TZIELD? Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:
  • have a serious infection or an infection that does not go away or keeps coming back
  • have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your doctor that you are receiving TZIELD before receiving a vaccine
  • are pregnant or plan to become pregnant. TZIELD may harm your unborn baby. Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy
  • are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of TZIELD? The most common side effects of TZIELD include:
  • rash
  • leukopenia (decrease in white blood cell counts)
  • headache

These are not all of the possible side effects of TZIELD. Talk to your healthcare provider for more information, and tell them about any side effects you notice. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

Please see Medication Guide and Prescribing Information.

What is TZIELD?

TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body can’t make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 8 years of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes.

It is not known if TZIELD is safe and effective in children under 8 years of age.