Resources to help you take action at every step
Explore helpful downloads and community organizations
Downloadable resources
Doctor Discussion Guide
Need help speaking to your doctor about TZIELD? This useful guide can help start the conversation about treatment.
Patient Brochure
The Patient Brochure is a helpful resource for learning more about TZIELD and how it can help delay the onset of insulin-dependent (Stage 3) T1D.
Infusion Guide
Get a comprehensive overview of the TZIELD infusion process, including what to expect before, during, and after treatment with TZIELD.
T1D Playbook
Make sure you’re ready for your TZIELD appointments with this action plan checklist.
AAb Results Explainer
Understand your autoantibody (AAb) results and what comes next with this guide.
Doctor Discussion Guide
Need help speaking to your doctor about TZIELD? This useful guide can help start the conversation about treatment.
Patient Brochure
The Patient Brochure is a helpful resource for learning more about TZIELD and how it can help delay the onset of insulin-dependent (Stage 3) T1D.
Infusion Guide
Get a comprehensive overview of the TZIELD infusion process, including what to expect before, during, and after treatment with TZIELD.
T1D Playbook
Make sure you’re ready for your TZIELD appointments with this action plan checklist.
AAb Results Explainer
Understand your autoantibody (AAb) results and what comes next with this guide.
Be a champion for your health—ask your doctor about screening
If you find out about T1D at the right time, you may have the power to do something about it. Talk to your doctor about screening for T1D today.
T1D organizations
You’re not alone. There is a world of support available to you in whatever form you need it, from online resources to in-person support groups. Below are a few helpful organizations to start exploring.
The American Diabetes Association is a network of more than half a million volunteers, people living with diabetes and their families, and healthcare professionals all united to improve the lives of people affected by diabetes.
These 3rd party links are provided for convenience and does not represent a recomendation or endorsement by Sanofi for the content on these websites
Breakthrough T1D is the leading global research organization funding type 1 diabetes research.
These 3rd party links are provided for convenience and does not represent a recomendation or endorsement by Sanofi for the content on these websites
Beyond Type 1 is a nonprofit organization changing what it means to live with diabetes.
These 3rd party links are provided for convenience and does not represent a recomendation or endorsement by Sanofi for the content on these websites
TCOYD is a nonprofit organization that provides educational live conferences and engaging digital programs for the diabetes community.
These 3rd party links are provided for convenience and does not represent a recomendation or endorsement by Sanofi for the content on these websites
Children with Diabetes® provides education and support to families living with T1D through its website and its Friends for Life® conferences.
These 3rd party links are provided for convenience and does not represent a recomendation or endorsement by Sanofi for the content on these websites
Getting Ahead of Type 1 is a collaborative effort focused on early detection and management of T1D through screening.
These 3rd party links are provided for convenience and does not represent a recomendation or endorsement by Sanofi for the content on these websites
The American Diabetes Association is a network of more than half a million volunteers, people living with diabetes and their families, and healthcare professionals all united to improve the lives of people affected by diabetes.
Breakthrough T1D is the leading global research organization funding type 1 diabetes research.
Beyond Type 1 is a nonprofit organization changing what it means to live with diabetes.
TCOYD is a nonprofit organization that provides educational live conferences and engaging digital programs for the diabetes community.
Children with Diabetes® provides education and support to families living with T1D through its website and its Friends for Life® conferences.
Getting Ahead of Type 1 is a collaborative effort focused on early detection and management of T1D through screening.
These third-party links are provided for convenience and do not represent a recommendation or endorsement by Sanofi for the content on these websites.
Have more general questions about T1D, screening, or TZIELD?
You can start a chat or choose to leave a message for one of our diabetes counselors to give you a call.
Get startedYour doctor is your best resource for specific questions you have about your health or treatments
Important Safety Information and Indication
What is the most important information I should know about TZIELD? TZIELD may cause serious side effects. These including:- Viral Reactivation. Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are common viruses that may stay inactive in your body after an initial infection. TZIELD may cause these viruses to become active again which, especially in patients with a weakened immune system, can become serious and potentially life-threatening. These viral reactivations can happen during treatment with TZIELD and up to 2 months after your last dose. Your healthcare provider will test you for active EBV and CMV infections before treatment with TZIELD. Contact your healthcare provider right away if you develop symptoms of an infection during or after treatment with TZIELD (such as fever, swollen glands, or fatigue).
- Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea (with or without vomiting), feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD.
- Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes.
Your healthcare provider will do blood tests to check for active infections, verify your liver function and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection or viral reactivation, or if your blood counts stay too low.
What should I tell my healthcare provider before receiving TZIELD? Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:- have any of the conditions or symptoms listed in the section “What is the most important information I should know about TZIELD?”
- have a weakened immune system, including if you have Down syndrome.
- have a serious infection or an infection that does not go away or keeps coming back (chronic).
- have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your healthcare provider that you are receiving treatment with TZIELD before receiving a vaccine.
- are pregnant or plan to become pregnant. TZIELD may harm your unborn baby. Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy.
If you become pregnant while taking TZIELD, you are encouraged to report your pregnancy to us at our Adverse Event reporting line at 1-800-633-1610 or visit https://ae.reporting.sanofi.
- are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of TZIELD? The most common side effects of TZIELD include:- decrease in white blood cell counts
- vomiting
- rash
- diarrhea
- headache
These are not all of the possible side effects of TZIELD. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to us at 1-800-633-1610 or www.fda.gov/medwatch or 1-800-FDA-1088.
Please see full Prescribing Information, including Risk of SERIOUS SIDE EFFECTS and Medication Guide.
What is TZIELD?
TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body cannot make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 1 year of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes or other forms of diabetes.
It is not known if TZIELD is safe and effective in children under 1 years of age.
Important Safety Information and Indication
- Viral Reactivation. Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are common viruses that may stay inactive in your body after an initial infection. TZIELD may cause these viruses to become active again which, especially in patients with a weakened immune system, can become serious and potentially life-threatening. These viral reactivations can happen during treatment with TZIELD and up to 2 months after your last dose. Your healthcare provider will test you for active EBV and CMV infections before treatment with TZIELD. Contact your healthcare provider right away if you develop symptoms of an infection during or after treatment with TZIELD (such as fever, swollen glands, or fatigue).
- Cytokine release syndrome (CRS). Signs and symptoms may start during the first 5 days of TZIELD treatment and could include fever, nausea (with or without vomiting), feeling tired (fatigue), headache, muscle and joint pain, or increased liver enzymes in your blood. Tell your healthcare provider right away if you develop any signs and symptoms of CRS during treatment with TZIELD.
- Decrease in white blood cells. TZIELD may cause a decrease in a type of white blood cell called lymphocytes. A decrease in white blood cells is a serious, but common side effect that can affect your body’s ability to fight infections. A decrease in white blood cell counts can happen after your first dose. Your white blood cell counts will start to go back to normal after your fifth dose of TZIELD. Some people may develop longer and more severe decreases in lymphocytes.
Your healthcare provider will do blood tests to check for active infections, verify your liver function and your complete blood counts before you start treatment and during treatment with TZIELD. During and after your treatment with TZIELD, your healthcare provider will check for serious side effects, as well as other side effects, and treat you as needed. Your healthcare provider may temporarily or completely stop your treatment with TZIELD, if you develop liver problems, have a serious infection or viral reactivation, or if your blood counts stay too low.
What should I tell my healthcare provider before receiving TZIELD? Before or after receiving TZIELD, tell your healthcare provider about all your medical conditions, including if you:- have any of the conditions or symptoms listed in the section “What is the most important information I should know about TZIELD?”
- have a weakened immune system, including if you have Down syndrome.
- have a serious infection or an infection that does not go away or keeps coming back (chronic).
- have recently received or are scheduled to receive an immunization (vaccine). TZIELD may affect how well a vaccine works. Tell your healthcare provider that you are receiving treatment with TZIELD before receiving a vaccine.
- are pregnant or plan to become pregnant. TZIELD may harm your unborn baby. Do not receive TZIELD during pregnancy and at least 30 days before a planned pregnancy.
If you become pregnant while taking TZIELD, you are encouraged to report your pregnancy to us at our Adverse Event reporting line at 1-800-633-1610 or visit https://ae.reporting.sanofi.
- are breastfeeding or plan to breastfeed. It is not known if TZIELD passes into your breast milk and if it can harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive TZIELD.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of TZIELD? The most common side effects of TZIELD include:- decrease in white blood cell counts
- vomiting
- rash
- diarrhea
- headache
These are not all of the possible side effects of TZIELD. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to us at 1-800-633-1610 or www.fda.gov/medwatch or 1-800-FDA-1088.
Please see full Prescribing Information, including Risk of SERIOUS SIDE EFFECTS and Medication Guide.
What is TZIELD?
TZIELD is a prescription medicine used to delay the onset of Stage 3 type 1 diabetes, which is when your body cannot make enough insulin on its own and may require insulin injections. TZIELD is for adults and children 1 year of age and older who have Stage 2 type 1 diabetes. This means that they have tested positive for 2 or more type 1 diabetes-related autoantibodies, have abnormal blood sugar levels, and do not have type 2 diabetes or other forms of diabetes.
It is not known if TZIELD is safe and effective in children under 1 years of age.